UCLA-Mellinkoff Gastroenterology and Hepatology Symposium
March 6-7, 2020
Learn more about the UCLA Vatche & Taman Manoukian Division of Digestive Disease at www.uclahealth.org/gastro
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History of every hundred years……
1720 _ Great Plague of Marseilles
1820 _ Cholera Outbreak
1920 _ Spanish Flu
2020 _ Corona Virus
1720 – the great plague of Marseilles –
this was the last significant European outbreak of the bubonic plague.
The great plague of Marseilles was the last of the significant European outbreaks of bubonic plague.
1820 _ cholera outbreak –
The story of the 1854 Broad Street cholera outbreak in London, and the man who made the breakthrough that brought it under control
1920 _ Spanish Flu –
the Spanish flu: the biggest pandemic in modern history.
why the 1918 Spanish flu probably didn’t originate in Spain.
Spanish flu: a warning from history. Yakima woman remembers Spanish flu of 1918, compares outbreak to coronavirus.
how the coronavirus pandemic compares to the Spanish flu | the new yorker. and how the response to coronavirus could avoid a repeat of ‘great influenza ‘ or the Spanish flu.
why Spanish flu killed over 50 million people – deadliest plague in modern history.
like the coronavirus, the Spanish flu was a global pandemic.
2020 _ Corona Virus –
cases in India rise to 13,835, death toll crosses 450-mark Coronavirus
On January 30, the World Health Organization declared the coronavirus outbreak a Global Public Health Emergency
What is happening | history follows a pattern every 100 years for epidemic diseases | coronavirus..
Corona virus| history follows a pattern every 100 years for epidemic diseases
History follows a pattern every 100 years for epidemic diseases | coronavirus 2020 in Hindi.
Maharishi | history follows a pattern every 100 years for epidemic disease.
History follows a pattern every 100 years |
Stay Home #With Me,100 years epidemic, epidemic diseases, history of epidemic diseases,100 years pattern of epidemic diseases.
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Diseases in Dungeons and Dragons 5E (A Doctor’s Overview)
Not every character in Dungeons and Dragons is as flawless as their player character make think they are. I go over the general rules of disease as a mechanic in Dungeons and Dragons 5e and share some real life similarities from an MD perspective.
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Staring, Edited and Written by: Christian Capanna
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In this World Anvil series we take a look at conditions such as diseases and how you can add it into your RPG world.
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Though many innocent souls were lost due to physical injuries sustained during battle , others suffered from diseases which arose from poor living conditions, food shortages, and lack of personal hygiene in the trenches. This meant that people were often admitted to hospital for sickness instead of wounds and medics found themselves fighting a war against disease as well as injury. It was a rare sight to see someone escape the war without some kind of injury or decline in their overall health. But lack of medicine and pharmaceutical knowledge meant that many diseases had no cure. If one person was infected, the disease would be instantly transmitted to those around them, which ultimately led to global epidemics and the death of countless people. Here is a list of the top 10 diseases that were common in World War I:
Top 10 Diseases That Were Common in World War I
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The conditions inside the trenches of WWI were not the best. This film talks about some of the diseases that the soldiers of WWI had to deal with.
By Chris Blea
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►👨🏫💊Antibiotics Lectures: https://www.medicosisperfectionalis.com/products/courses/antibiotics/ … Check out my brand new “Electrolytes” course at https://www.medicosisperfectionalis.com/products/course/electrolytes/ and use the PROMO code: ELECTROLYTES50 to get a 50% discount. Anti-neutrophilic cytoplasmic antibodies (ANCA) are IgG autoantibodies against the cytoplasm of the neutrophils and monocytes.
This is different from antinuclear antibodies (ANA) which are antibodies against the nucleus.
Anti-neutrophilic cytoplasmic antibodies (ANCA) have several patterns; the most important two being the cytoplasmic ANCA (c-ANCA) and the perinuclear ANCA (p-ANCA).
Anti-neutrophilic cytoplasmic antibodies (ANCA) are associated with vasculitis, such as granulomatosis with polyangiitis (Wegener granulomatosis), microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Strauss), rapidly-progressive glomerulonephritis (RPGN), anti-glomerular basement membrane antibodies (ant-GBM or Goodpasture’s syndrome), as well as inflammatory bowel disease-associated. vasculitis.
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In brief, Anti-neutrophilic cytoplasmic antibodies (ANCA) are IgG autoantibodies against the cytoplasm of the neutrophils and monocytes, and are associated with vasculitis, but they don’t correlate with disease activity or symptoms. If you like my videos, please consider leaving a tip at https://www.paypal.me/perfectionalis/
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“Small Vessel Vasculitis Vasculitis is inflammation of the blood vessels resulting in damaged vessels leading to potential complication such as tissue ischaemia from lumen narrowing or from thromboembolic events from platelet consumption during vessel repair. Primary vasculitides are classified into the size of the blood vessels affected; large vessel, medium vessel and small vessel vasculitis. The small vessel vasculitis can be further divided into ANCA associated vasculitis (AAVs) and immune complex mediated vasculitis.
ANCA associated vasculitis is so called this because in the person’s blood there is presence of ANCA which is an abbreviated to antineutrophil cytoplasmic antibody. AAVs usually tends to affect small and medium sized arteries. There are three main types of ANCA
– Microscopic polyangiitis
– Granulomatosis with polyangiitis
– Eosinophilic granulomatosis with polyangiitis
The pathophysiology of AAV involve presence of ANCA and also granulomatosis.
ANCA target certain proteins in the cytoplasmic granules of neutrophils and monocytes. The neutrophil for example contains enzymes myeloperoxidase and proteinase 3 in granules. What it thought to happen is that during inflammation cytokines such as TNFa and IL1 stimulates the translocation of proteinase 3 and myeloperixoidase to the cell membrane allowing these enzymes to be exposed.”
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Throughout history, there have always been outbreaks of diseases. Which ones were the worst? Join Laci as she breaks down the top 5 deadliest pandemic diseases.
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A worried world watches as Ebola death toll rises; Liberia declares emergency
http://www.cnn.com/2014/08/06/health/africa-ebola-outbreak/index.html
“With the World Health Organization announcing Wednesday that 932 deaths had been reported or confirmed as a result of Ebola hemorrhagic fever, Saudi Arabia joined the list of countries with suspected cases.”
Smallpox Disease Overview
http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp
“Smallpox is a serious, contagious, and sometimes fatal infectious disease. There is no specific treatment for smallpox disease, and the only prevention is vaccination.”
World Health Organization declares smallpox eradicated
http://www.pbs.org/wgbh/aso/databank/entries/dm79sp.html
“One of the twentieth century’s greatest victories in medicine began in 1796. That year Edward Jenner discovered vaccination. It was known that if a person had smallpox and survived, he or she would not get the disease again.”
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How We Eradicated Smallpox
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Preventative vaccines have eradicated various diseases over the decades. Here are some of them.
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Kindly note that an average between every 100 years is given for all major epidemic diseases. Please see the description for accurate years and check the link from Wikipedia for sources
https://en.m.wikipedia.org/wiki/List_of_epidemics
1720-The Great Plague of Marseille
The disease arrived on a merchant ship called the Grand Saint Antoine at French port city of Marseille. It carried infected passengers from Middle East and unloaded its cargo which contained rat fleas. Plague-carrying rat fleas soon spread across the city, sparking an epidemic. Plague walls” were even built to try to and contain the infection, but it still spilled over into southern France before finally disappearing in 1722. By then, it had killed roughly 100,000 people.
1817-1824 (Cholera)- average (1820)
The first cholera pandemic 1820 also known as the first Asiatic cholera pandemic or Asiatic cholera, began near the city of Calcutta (India) stemming from contaminated rice and spread throughout Southeast Asia to the Middle East, eastern Africa and the Mediterranean coast. Cholera highest death rate was in Thailand, Indonesia (killing 100,000 people on the island of Java alone) and the Philippines.
1918-1919 (Spanish Flu)- average (1920)
France was the epic centre of Spanish flu. It first originated in a hospital, overcrowded camp which was an ideal site for the spreading of a respiratory virus. The hospital treated thousands of victims of chemical attacks, and other casualties of war, and 100,000 soldiers passed through the camp every day. It also was home to a piggery, and poultry was regularly brought in for food supplies from surrounding villages. Significant precursor virus, harbored in birds, mutated and then migrated to pigs kept near the front. The death toll is estimated to have been anywhere from 50 million to100 million, making it one of the deadliest epidemics in human history
2019-2020 (Coronaviru)- average (2020)
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History Follows a Pattern Every 100 Years for Epidemic Diseases | Corona | TVNXT Telugu
#Corona #Plague #Cholera #Spanish Flu #Sars #Ebola
1720-The Great Plague of Marseille
The disease arrived on a merchant ship called the Grand Saint Antoine at the French port city of Marseille. It carried infected passengers from the Middle East and unloaded its cargo which contained rat fleas. Plague-carrying rat fleas soon spread across the city, sparking an epidemic. Plague walls” were even built to try to and contain the infection, but it still spilled over into southern France before finally disappearing in 1722. By then, it had killed roughly 100,000 people.
1817-1824 (Cholera)- average (1820)
The first cholera pandemic 1820 also known as the first Asiatic cholera pandemic or Asiatic cholera, began near the city of Calcutta (India) stemming from contaminated rice and spread throughout Southeast Asia to the Middle East, eastern Africa and the Mediterranean coast. Cholera’s highest death rate was in Thailand, Indonesia (killing 100,000 people on the island of Java alone) and the Philippines.
1918-1919 (Spanish Flu)- average (1920)
France was the epic center of Spanish flu. It first originated in a hospital, an overcrowded camp which was an ideal site for the spreading of a respiratory virus. The hospital treated thousands of victims of chemical attacks, and other casualties of war and 100,000 soldiers passed through the camp every day. It also was home to a piggery, and poultry was regularly brought in for food supplies from surrounding villages. Significant precursor virus, harbored in birds, mutated and then migrated to pigs kept near the front. The death toll is estimated to have been anywhere from 50 million to100 million, making it one of the deadliest epidemics in human history
2019-2020 (Coronavirus)- average (2020)
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