Take a look at what Communicable diseases are, what causes them and how they are transmitted.
The National Institute for Communicable Diseases is a resource of knowledge and expertise in regionally relevant communicable diseases to the South African Government, to SADC countries and the African continent.
#CommunicableDiseases #InfectiousDiseases #NICD Video Rating: / 5
Hepatitis C, often abbreviated HCV, is a DNA virus that is most often transmitted by the sharing of infected needles. It can often lead to serious liver conditions if left untreated. Join Dr. Dominic Rowley as he explains the virus in detail.
See below for an overview of points covered in this video.
For more information please navigate to:
https://www.letsgetchecked.com/sti-testing/?utm_source=youtube&utm_medium=video&utm_campaign=Rowley_Videos_YT&utm_term=Hepatitis%20C&utm_content=video%20description
0:10 – What is hepatitis C?
0:30 – How is hepatitis C transmitted?
1:26 – Hepatitis C, symptoms and complications?
2:11 – What is the test for hepatitis B?
2:50 – How to get tested?
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Have you ever thought about the effects Hepatitis C (HCV) may have on individuals? Did you ever think about whether or not the disease can be fatal? Be sure to watch this video to make sure you find out the molecular mechanisms of the disease, symptoms, and methods of transmission in place. This video will give you insight of statistics in Canada as well as globally on cure rate, survival rate, and death rates of HCV.
Kindly click the following link for the video transcript with timestamps:
https://docs.google.com/document/d/12PP-CMdLAqx-wrPyAS-_xfFUS7dvye2T293T2RM9Aao/e dit?usp=sharing
This video was made by McMaster Demystifying Medicine students: Abdel-Rahman Mohamed-El Faki, Maiura Muralitharan, and Mansi Patel in collaboration with the McMaster Demystifying Medicine Program.
Copyright McMaster University 2020
References:
1. Canada, P. (2018, June 07). Government of Canada. Retrieved November 08, 2020, from
https://www.canada.ca/en/public-health/services/reports-publications/canada-communic able-disease-report-ccdr/monthly-issue/2018-44/issue-7-8-july-5-2018/article-7-hepatitis- c-canada-2018-infographic.html
2. Canada, P. (2020, August 14). Government of Canada. Retrieved November 08, 2020, from https://www.canada.ca/en/public-health/services/diseases/hepatitis-c.html
3. Commissioner, O. (n.d.). Hepatitis C Treatments Give Patients More Options. Retrieved November 08, 2020, from https://www.fda.gov/consumers/consumer-updates/hepatitis-c-treatments-give-patients- more-options
4. Carrat, F., Fontaine, H., Dorival, C., Simony, M., Diallo, A., Hezode, C., … & Zoulim, F. (2019). Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study. The Lancet, 393(10179), 1453-1464. doi: https://doi.org/10.1016/S0140-6736(18)32111-1
5. Gale, M., Blakely, C. M., Kwieciszewski, B., Tan, S. L., Dossett, M., Tang, N. M., … & Katze, M. G. (1998). Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Molecular and cellular biology,
18( 9), 5208-5218. doi: 10.1128/MCB.18.9.5208
6. Ghany, M. G., Marks, K. M., Morgan, T. R., Wyles, D. L., Aronsohn, A. I., Bhattacharya, D., … & Heller, T. (2019). Hepatitis C guidance 2019 update: AASLD-IDSA recommendations for testing, managing, and treating hepatitis C virus infection. Hepatology, 71(2), 686-721. doi: 10.1002/hep.31060
7. Hepatitis C Symptoms. Diagnosing Hepatitis C – ALF. (2020, March 10). Retrieved
November 08, 2020, from https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/hepatitis-c/dia gnosing-hepatitis-c/
8. Hepatitis C Treatment. Treatment for Hepatitis C Info – ALF. (2020, April 13). Retrieved November 08, 2020, from https://liverfoundation.org/for-patients/about-the-liver/diseases-of-the-liver/hepatitis-c/trea ting-hepatitis-c/
9. National Progress Report 2025 Goal: Reduce reported rate of hepatitis C-related deaths by ≥20%. (2020, August 11). Retrieved November 08, 2020, from https://www.cdc.gov/hepatitis/policy/NationalProgressReport-HepC-ReduceDeaths.htm
10. Khatun, M., & Ray, R. B. (2019). Mechanisms underlying hepatitis C Virus-associated hepatic fibrosis. Cells, 8( 10), 1249. doi: https://doi.org/10.3390/cells8101249
11. Owens, D. K., Davidson, K. W., Krist, A. H., Barry, M. J., Cabana, M., Caughey, A. B., … & Ogedegbe, G. (2020). Screening for hepatitis C virus infection in adolescents and adults: US Preventive Services Task Force recommendation statement. Jama, 323(10), 970-975. doi: 10.1001/jama.2020.1123
12. Schillie, S., Wester, C., Osborne, M., Wesolowski, L., & Ryerson, A. B. (2020). CDC recommendations for hepatitis C screening among adults—United States, 2020. MMWR Recommendations and Reports, 69( 2), 1. doi: 10.15585/mmwr.rr6902a1
13. van de Laar, T. J., van der Bij, A. K., Prins, M., Bruisten, S. M., Brinkman, K., Ruys, T. A., … & Jurriaans, S. (2007). Increase in HCV incidence among men who have sex with men in Amsterdam most likely caused by sexual transmission. The Journal of infectious diseases, 196( 2), 230-238. doi: https://doi.org/10.1086/518796
14. Vescovo, T., Refolo, G., Vitagliano, G., Fimia, G. M., & Piacentini, M. (2016). Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma. Clinical Microbiology and Infection, 22( 10), 853-861. doi: https://doi.org/10.1016/j.cmi.2016.07.019
15. Zeisel, M. B., Fofana, I., Fafi-Kremer, S., & Baumert, T. F. (2011). Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies. Journal of hepatology, 54(3), 566-576. doi: https://doi.org/10.1016/j.jhep.2010.10.014
Credits:
The HCV life cycle animations were adapted from
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Vitamin D. This weeks video is on Vitamin D Foods. Vitamin D Deficiency Symptoms. Vitamin D Supplements, Benefits.
00:00 Vitamin D
01:09 Where does Vitamin D come from?
03:22 Vitamin D Foods
05:21 Vitamin D Deficiency Symptoms
06:18 Vitamin D Supplements
One of my favourite notifications is your comments and as you may already know more often than not I’ll get back to you with a reply and heart. If you’d like more information on any of the questions I’ve answered or have a question, then let me know so I can try and either dedicate a video to it or get back to you in next months responding to your comments.
VITAMIN D:
Vitamin D helps regulate the amount of calcium and phosphate in the body.
These nutrients are needed to keep bones, teeth and muscles healthy.
A lack of vitamin D can lead to bone deformities such as rickets in children, and bone pain caused by a condition called osteomalacia in adults.
For more information about Vitamin D – https://www.bda.uk.com/resource/vitamin-d.html
VITAMIN D AND SUNSHINE:
Unfortunately, the amount of Vitamin D your skin can make from sunlight varies a lot. It depends on your skin tone and how long you spend in the sun. Therefore I do not recommend that this is the only way you get Vitamin D.
Remember, UVB rays in sunlight cause skin damage and skin cancer – so do not depend on the sun for your Vitamin D – it is simply not worth it!
Sunscreen is really important and if you’re ever unsure about which sunscreen to wear and the science behind it the good news is I have a video on this already – https://www.youtube.com/watch?v=Lf5vsdcJMzQ
VITAMIN D FOODS:
Your next best source of Vitamin D is food. Foods high in Vitamin D include egg yolks and oily fish like salmon. Here’s a really useful page with a good list of Vitamin D foods – https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
Let me know what you find in the comments below!
You might have heard of foods “fortified with Vitamin D” – this means Vitamin D has been added to the food during the manufacturing process . Fortified foods include cereals, fat spreads and non-dairy milks.
In the UK, cows’ milk is generally not a good source of vitamin D because it is not fortified, as it is in some other countries.
Here’s a fun fact for you: You can now get super mushrooms that have been treated with UVB rays to make them high in vitamin D! Tomatoes, potatoes and peppers claim to be high in Vitamin D but sadly that’s not true.
VITAMIN D DEFFIECNY SYMPTOMS:
Symptoms of a Vitamin D deficiency include feeling tired and weak. You might also experience muscle and joint or bone pains.
Vitamin D deficiency in children causes rickets – also known as soft or bendy bones, and in adults this is known as osteomalacia. For more information on this – https://www.nhs.uk/conditions/rickets-and-osteomalacia/
PEOPLE AT RISK OF VITAMIN D DEFICIENCY:
As mentioned in the video some people will not get enough vitamin D from sunlight because they have very little or no sunshine exposure.
The Department of Health and Social Care recommends that you take a daily supplement containing 10 micrograms of vitamin D throughout the year if you:
• Are not often outdoors – for example, if you’re frail or housebound
• Are in an institution like a care home
• Usually wear clothes that cover up most of your skin when outdoors
• If you have dark skin – for example you have an African, African-Caribbean or south Asian background – you may also not get enough vitamin D from sunlight.
You should consider taking a daily supplement containing 10 micrograms of vitamin D throughout the year.
Want to see more videos about everything health and pharmacy? Let me know in the comments below. Subscribe for new videos ▶https://www.youtube.com/c/AbrahamThePharmacist
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ABOUT ME:
Prescribing Media Pharmacist | Extreme Optimist | Bringing Science Through New Videos Every Week – Monday 4PM(GMT).
I’m a prescribing media pharmacist who loves science, making videos and helping people. I work in both GP surgeries and community pharmacy.
DISCLAIMER:
This video is for information only and should not be used for the diagnosis or treatment of medical conditions. Abraham The Pharmacist has used all reasonable care in compiling the information but make no warranty as to its accuracy. Always consult a doctor or other healthcare professional for diagnosis and treatment of medical conditions. Video Rating: / 5
Inside the warehouse of Pharmapacks, a company that took on Amazon and eBay by constantly changing prices to get consumers better deals. Video Rating: / 5
Consumers are shifting their spending from in-store to online making an e-commerce presence critical for businesses to stay afloat. Many businesses are relying on platforms like cloud-based Shopify, which has jumped 73% since the WHO declared a pandemic in mid-March. Shopify powers sites for 1 million brands, including Allbirds, Staples and PepsiCo. Harley Finkelstein, Shopify chief operating officer, joins “Squawk Box” to discuss.
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UCLA-Mellinkoff Gastroenterology and Hepatology Symposium
March 6-7, 2020
Learn more about the UCLA Vatche & Taman Manoukian Division of Digestive Disease at www.uclahealth.org/gastro Video Rating: / 5